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Article

Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide.

American journal of physiology. Endocrinology and metabolism - 1 Sept 2008

Dungan Lemko Heather M, Clifton Donald K, Steiner Robert A, Fraley Gregory S

Abstract excerpt

Galanin-like peptide (GALP) is expressed in the arcuate nucleus and is implicated in the neuroendocrine regulation of metabolism and reproduction. To investigate the physiological significance of GALP, we generated and characterized a strain of mice with a genetically targeted deletion in the GALP gene [GALP knockout (KO) mice]. We report that GALP KO mice have a subtle, but notable, metabolic phenotype that...

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Identifiers

PMID: 18775887
DOI: 10.1152/ajpendo.90425.2008
PMCID: PMC2536739

Genes

GALP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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