Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.

doi:10.1016/j.celrep.2019.12.043

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Article

Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.

Cell reports - 21 Jan 2020

Nayak Gowri, Zhang Kevin X, Vemaraju Shruti, Odaka Yoshinobu, Buhr Ethan D, Holt-Jones Amanda, Kernodle Stace, Smith April N, Upton Brian A, D'Souza Shane, Zhan Jesse J, Diaz Nicolás, Nguyen Minh-Thanh, Mukherjee Rajib, Gordon Shannon A, Wu Gang, Schmidt Robert, Mei Xue, Petts Nathan T, Batie Matthew, Rao Sujata, Hogenesch John B, Nakamura Takahisa, Sweeney Alison, Seeley Randy J, Van Gelder Russell N, Sanchez-Gurmaches Joan, Lang Richard A

Abstract excerpt

Almost all life forms can detect and decode light information for adaptive advantage. Examples include the visual system, in which photoreceptor signals are processed into virtual images, and the circadian system, in which light entrains a physiological clock. Here we describe a light response pathway in mice that employs encephalopsin (OPN3, a 480 nm, blue-light-responsive opsin) to regulate the function of...

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PMID: 31968245
DOI: 10.1016/j.celrep.2019.12.043
PMCID: PMC7341981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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