Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.

doi:10.1007/s00125-017-4282-7

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Article

Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.

Diabetologia - 1 Jul 2017

Laperrousaz Elise, Moullé Valentine S, Denis Raphaël G, Kassis Nadim, Berland Chloé, Colsch Benoit, Fioramonti Xavier, Philippe Erwann, Lacombe Amélie, Vanacker Charlotte, Butin Noémie, Bruce Kimberley D, Wang Hong, Wang Yongping, Gao Yuanqing, Garcia-Caceres Cristina, Prévot Vincent, Tschöp Matthias H, Eckel Robert H, Le Stunff Hervé, Luquet Serge, Magnan Christophe, Cruciani-Guglielmacci Céline

Abstract excerpt

AIMS/HYPOTHESIS: Regulation of energy balance involves the participation of many factors, including nutrients, among which are circulating lipids, acting as peripheral signals informing the central nervous system of the energy status of the organism. It has been shown that neuronal lipoprotein lipase (LPL) participates in the control of energy balance by hydrolysing lipid particles enriched in triacylglycerols....

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PMID: 28456865
DOI: 10.1007/s00125-017-4282-7

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