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Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell Carcinoma

2 Dec 2021

Abstract excerpt

Background Renal cell carcinoma (RCC) is a disease of genomic alterations, of which the complete panorama helps in facilitating molecular-guided therapy. Germline mutation profiles and associated somatic and clinical characteristics remains unexplored in Chinese RCC patients. Methods We retrospectively profiled the germline and somatic mutations of 322 unselected RCC patients using a panel consisting of 808...

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PMID: 34926252
DOI: 10.3389/fonc.2021.737547

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