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Article

Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.

Cancer research - 15 Feb 2006

Banks Rosamonde E, Tirukonda Prasanna, Taylor Claire, Hornigold Nick, Astuti Dewi, Cohen Dena, Maher Eamonn R, Stanley Anthea J, Harnden Patricia, Joyce Adrian, Knowles Margaret, Selby Peter J

Abstract excerpt

Genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumor suppressor gene are common in sporadic conventional renal cell carcinoma (cRCC). Further insight into the clinical significance of these changes may lead to increased biological understanding and identification of subgroups of patients differing prognostically or who may benefit from specific targeted treatments. We have comprehensively examined...

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Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

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Share to Promoter Regions, Genetic

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 16488999
DOI: 10.1158/0008-5472.CAN-05-3074

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.PMID 16488999Read ↗

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