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Article

Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk.

Genetic epidemiology - 1 May 2014

Hellwege Jacklyn N, Palmer Nicholette D, Raffield Laura M, Ng Maggie C Y, Hawkins Gregory A, Long Jirong, Lorenzo Carlos, Norris Jill M, Ida Chen Y-D, Speliotes Elizabeth K, Rotter Jerome I, Langefeld Carl D, Wagenknecht Lynne E, Bowden Donald W

Abstract excerpt

Linkage analysis of complex traits has had limited success in identifying trait-influencing loci. Recently, coding variants have been implicated as the basis for some biomedical associations. We tested whether coding variants are the basis for linkage peaks of complex traits in 42 African-American (n = 596) and 90 Hispanic (n = 1,414) families in the Insulin Resistance Atherosclerosis Family Study (IRASFS) using...

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Source

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Identifiers

PMID: 24719370
DOI: 10.1002/gepi.21801
PMCID: PMC4281959

Genes

CETP
MAF
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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