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Article

Transferability and fine mapping of genome-wide associated loci for lipids in African Americans.

BMC medical genetics - 21 Sept 2012

Adeyemo Adebowale, Bentley Amy R, Meilleur Katherine G, Doumatey Ayo P, Chen Guanjie, Zhou Jie, Shriner Daniel, Huang Hanxia, Herbert Alan, Gerry Norman P, Christman Michael F, Rotimi Charles N

Abstract excerpt

BACKGROUND: A recent, large genome-wide association study (GWAS) of European ancestry individuals has identified multiple genetic variants influencing serum lipids. Studies of the transferability of these associations to African Americans remain few, an important limitation given interethnic differences in serum lipids and the disproportionate burden of lipid-associated metabolic diseases among African Americans....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22994408
DOI: 10.1186/1471-2350-13-88
PMCID: PMC3573912

Genes

ANGPTL3
APOE
CETP
CILP2
DOCK7
IRS1
LPL
SORT1
STARD3

Provenance

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