Article
Cell movements of the deep layer of non-neural ectoderm underlie complete neural tube closure in Xenopus.
Development (Cambridge, England) - 1 Apr 2012
Morita Hitoshi, Kajiura-Kobayashi Hiroko, Takagi Chiyo, Yamamoto Takamasa S, Nonaka Shigenori, Ueno Naoto
Abstract excerpt
In developing vertebrates, the neural tube forms from a sheet of neural ectoderm by complex cell movements and morphogenesis. Convergent extension movements and the apical constriction along with apical-basal elongation of cells in the neural ectoderm are thought to be essential for the neural tube closure (NTC) process. In addition, it is known that non-neural ectoderm also plays a crucial role in this process,...
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