Article
Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 May 2014
Harmon Quaker E, Engel Stephanie M, Wu Michael C, Moran Thomas M, Luo Jingchun, Stuebe Alison M, Avery Christy L, Olshan Andrew F
Abstract excerpt
PROBLEM: Inflammatory biomarkers are associated with preeclampsia (PE) and poor fetal growth; however, genetic epidemiologic studies have been limited by reduced gene coverage and the exclusion of African American mothers. METHOD OF STUDY: Cases and controls (N = 1646) from a pregnancy cohort were genotyped for 503 tagSNPs in 40 genes related to inflammation. Gene-set analyses were stratified by race and were...
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