Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

doi:10.1016/j.ajog.2010.03.026

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Article

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

American journal of obstetrics and gynecology - 1 May 2010

Romero Roberto, Velez Edwards Digna R, Kusanovic Juan Pedro, Hassan Sonia S, Mazaki-Tovi Shali, Vaisbuch Edi, Kim Chong Jai, Chaiworapongsa Tinnakorn, Pearce Brad D, Friel Lara A, Bartlett Jacquelaine, Anant Madan Kumar, Salisbury Benjamin A, Vovis Gerald F, Lee Min Seob, Gomez Ricardo, Behnke Ernesto, Oyarzun Enrique, Tromp Gerard, Williams Scott M, Menon Ramkumar

Abstract excerpt

OBJECTIVE: The purpose of this study was to determine whether maternal/fetal single nucleotide polymorphisms (SNPs) in candidate genes are associated with spontaneous preterm labor/delivery. STUDY DESIGN: A genetic association study was conducted in 223 mothers and 179 fetuses (preterm labor with intact membranes who delivered <37 weeks of gestation [preterm birth (PTB)]), and 599 mothers and 628 fetuses (normal...

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Identifiers

PMID: 20452482
DOI: 10.1016/j.ajog.2010.03.026
PMCID: PMC3604889

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