Article
Effect of interleukin-6 polymorphism on risk of preterm birth within population strata: a meta-analysis.
BMC genetics - 25 Apr 2013
Wu Wilfred, Clark Erin A S, Stoddard Gregory J, Watkins W Scott, Esplin M Sean, Manuck Tracy A, Xing Jinchuan, Varner Michael W, Jorde Lynn B
Abstract excerpt
BACKGROUND: Because of the role of inflammation in preterm birth (PTB), polymorphisms in and near the interleukin-6 gene (IL6) have been association study targets. Several previous studies have assessed the association between PTB and a single nucleotide polymorphism (SNP), rs1800795, located in the IL6 gene promoter region. Their results have been inconsistent and SNP frequencies have varied strikingly among...
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