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Article

Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.

American journal of obstetrics and gynecology - 1 Feb 2009

Velez Digna R, Fortunato Stephen, Thorsen Poul, Lombardi Salvatore J, Williams Scott M, Menon Ramkumar

Abstract excerpt

OBJECTIVE: The objective of the study was to study the genetic risk factors of spontaneous preterm birth (PTB) in African Americans. STUDY DESIGN: Case-control analyses were performed using maternal and fetal deoxyribonucleic acid from 279 African American birth events (82 PTB and 197 term) and 1432 single-nucleotide polymorphisms from 130 candidate genes. Single-locus association and haplotype analyses were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19019335
DOI: 10.1016/j.ajog.2008.08.051
PMCID: PMC4829203

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