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Article

Genetic Variants Associated With Preeclampsia and Maternal Serum sFLT1 Levels.

Hypertension (Dallas, Tex. : 1979) - 1 May 2025

Mack Jasmine A, Sovio Ulla, Day Felix R, Gaccioli Francesca, Cook Emma, Bayzid Nadua, Cotic Marius, Dunton Nathan J, Madhan Gaganjit, Motsinger-Reif Alison A, Perry John R B, Charnock-Jones D Stephen, Smith Gordon C S

Abstract excerpt

BACKGROUND: Elevated maternal serum sFLT1 (soluble fms-like tyrosine kinase 1) has a key role in the pathophysiology of preeclampsia. We sought to determine the relationship between the maternal and fetal genome and maternal levels of sFLT1 at 12, 20, 28, and 36 weeks of gestational age (wkGA). METHODS: We studied a prospective cohort of nulliparous women (3968 mother-child pairs). We related maternal and fetal...

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Source

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Identifiers

PMID: 39723542
DOI: 10.1161/HYPERTENSIONAHA.124.23400
PMCID: PMC7617282

Genes

FLT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Genetic Variants Associated With Preeclampsia and Maternal Serum sFLT1 Levels.PMID 39723542Read ↗

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