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Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth.

Acta obstetricia et gynecologica Scandinavica - 1 Jan 2008

Hollegaard Mads Vilhelm, Grove Jakob, Thorsen Poul, Wang Xiaobin, Mandrup Susanne, Christiansen Michael, Norgaard-Pedersen Bent, Wojdemann Karen R, Tabor Ann, Attermann Jorn, Hougaard David Michael

Abstract excerpt

OBJECTIVE: To investigate the relation between 19 selected single nucleotide polymorphisms in three cytokine genes, tumor necrosis factor alpha (TNFA), interleukin 1-beta (IL1B) and interleukin 6 (IL6) and preterm birth (<37 weeks' gestation). DESIGN: Case-control association study. SAMPLE: A total of 117 singleton pregnant Danish Caucasian women, including 62 preterm birth cases and 55 controls (birth>or=37...

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PMID: 18951205
DOI: 10.1080/00016340802468340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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