Article
Polymorphisms in Inflammatory Mediator Genes and Risk of Preeclampsia in Taiyuan, China.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2017
Wu Weiwei, Yang Hailan, Feng Yongliang, Zhang Ping, Li Shuzhen, Wang Xin, Peng Tingting, Wang Fang, Xie Bingjie, Guo Pengge, Li Mei, Wang Ying, Zhao Nan, Wang Suping, Zhang Yawei
Abstract excerpt
Excessive maternal inflammatory response is involved in the pathogenesis of preeclampsia. Few epidemiologic studies have investigated the associations between genetic variations in the inflammatory mediator genes and preeclampsia risk, and these studies have reached inconsistent results. We examined 31 single-nucleotide polymorphisms in IL-1A, IL-1B, IL-1R1, IL-2RA, IL-5RA, IL-6, IL-6R, TNFSF11, TNFRSF11A,...
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