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Article

Unique and shared functions of nuclear lamina LEM domain proteins in Drosophila.

Genetics - 1 Jun 2014

Barton Lacy J, Wilmington Shameika R, Martin Melinda J, Skopec Hannah M, Lovander Kaylee E, Pinto Belinda S, Geyer Pamela K

Abstract excerpt

The nuclear lamina is an extensive protein network that contributes to nuclear structure and function. LEM domain (LAP2, emerin, MAN1 domain, LEM-D) proteins are components of the nuclear lamina, identified by a shared ∼45-amino-acid motif that binds Barrier-to-autointegration factor (BAF), a chromatin-interacting protein. Drosophila melanogaster has three nuclear lamina LEM-D proteins, named Otefin (Ote),...

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Identifiers

PMID: 24700158
DOI: 10.1534/genetics.114.162941
PMCID: PMC4063922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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