members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.

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Article

members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.

Genes & development - 1 Aug 2000

Uv A E, Roth P, Xylourgidis N, Wickberg A, Cantera R, Samakovlis C

Abstract excerpt

Many developmental and physiological responses rely on the selective translocation of transcriptional regulators in and out of the nucleus through the nuclear pores. Here we describe the Drosophila gene members only (mbo) encoding a nucleoporin homologous to the mammalian Nup88. The phenotypes of mbo mutants and mbo expression during development are cell specific, indicating that the nuclear import capacity of...

Topics

Amino Acid Sequence
Animals
Biological Transport
Cell Nucleus
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
Larva
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Nuclear Pore Complex Proteins

Nuclear Proteins

Phosphoproteins

RNA, Messenger

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 10921908
PMCID: PMC316830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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