Article
Drosophila male and female germline stem cell niches require the nuclear lamina protein Otefin.
Developmental biology - 1 Jul 2016
Barton Lacy J, Lovander Kaylee E, Pinto Belinda S, Geyer Pamela K
Abstract excerpt
The nuclear lamina is an extensive protein network that underlies the inner nuclear envelope. This network includes the LAP2-emerin-MAN1-domain (LEM-D) protein family, proteins that share an association with the chromatin binding protein Barrier-to-autointegration factor (BAF). Loss of individual LEM-D proteins causes progressive, tissue-restricted diseases, known as laminopathies. Mechanisms associated with...
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