Article
Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila.
Journal of cell science - 15 Sept 2003
Furukawa Kazuhiro, Sugiyama Shin, Osouda Shinichi, Goto Hidemasa, Inagaki Masaki, Horigome Tsuneyoshi, Omata Saburo, McConnell Maeve, Fisher Paul A, Nishida Yasuyoshi
Abstract excerpt
Barrier-to-autointegration factor (BAF) is potentially a DNA-bridging protein, which directly associates with inner nuclear membrane proteins carrying LEM domains. These features point to a key role in regulation of nuclear function and organization, dependent on interactions between the nuclear envelope and chromatin. To understand the functions of BAF in vivo, Drosophila baf null mutants generated by...
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