Article
A comparative study of Drosophila and human A-type lamins.
PloS one - 26 Oct 2009
Schulze Sandra R, Curio-Penny Beatrice, Speese Sean, Dialynas George, Cryderman Diane E, McDonough Caitrin W, Nalbant Demet, Petersen Melissa, Budnik Vivian, Geyer Pamela K, Wallrath Lori L
Abstract excerpt
Nuclear intermediate filament proteins, called lamins, form a meshwork that lines the inner surface of the nuclear envelope. Lamins contain three domains: an N-terminal head, a central rod and a C-terminal tail domain possessing an Ig-fold structural motif. Lamins are classified as either A- or B-type based on structure and expression pattern. The Drosophila genome possesses two genes encoding lamins, Lamin C and...
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