Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thiazide-induced hyponatraemia: epidemiology and clues to pathogenesis.

Cardiovascular therapeutics - 1 Oct 2012

Glover Mark, Clayton Jenny

Abstract excerpt

Thiazide diuretics are one of the most widely used and cost-effective classes of antihypertensive agents worldwide. Thiazides however have a significant side effect profile and are frequently insufficient to normalize blood pressure alone. Thiazide-induced hyponatraemia (TIH) is a major adverse effect, affecting up to one in seven patients receiving these drugs. TIH is more common in females, the elderly and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Aquaporins
Share to Diuretics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Sodium

Share to Sodium Chloride Symporters

Source

Identifiers

PMID: 21884020
DOI: 10.1111/j.1755-5922.2011.00286.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thiazide-induced hyponatraemia: epidemiology and clues to pathogenesis.PMID 21884020Read ↗

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia.Semantic proximity Read ↗

Genetic Determinants of Thiazide-Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances - A Genome-Wide Evaluation of the UK Biobank.Semantic proximity Read ↗

Molecular insights from dysregulation of the thiazide-sensitive WNK/SPAK/NCC pathway in the kidney: Gordon syndrome and thiazide-induced hyponatraemia.Semantic proximity Read ↗

Thiazide-sensitive Na+-Cl- cotransporter: genetic polymorphisms and human diseases.Semantic proximity Read ↗

The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population.Semantic proximity Read ↗

Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.Semantic proximity Read ↗

Serum chloride : epidemiology and genetic dissection of a novel marker for cardiovascular riskSemantic proximity Read ↗

Potassium-related inherited tubulopathies.Semantic proximity Read ↗

Pathophysiological role of Na-Cl cotransporter in kidneys, blood pressure, and metabolism.Semantic proximity Read ↗

The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.Semantic proximity Read ↗

Monogenic hypertension.Semantic proximity Read ↗

[Electrolyte disorders as a hallmark of monogenetic diseases].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.