Serotonin transporter polymorphic region 5-HTTLPR modulates risk for Parkinson's disease.

doi:10.1016/j.neurobiolaging.2014.03.002

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Article

Serotonin transporter polymorphic region 5-HTTLPR modulates risk for Parkinson's disease.

Neurobiology of aging - 1 Aug 2014

Zhang Xiong, Cheng Xing, Hu Yan-Bing, Lai Jun-Mei, You Hui, Hu Pei-Long, Zou Ming, Zhu Jian-Hong

Abstract excerpt

The association between the serotonin transporter gene (SLC6A4) polymorphisms, that is, 5-HTTLPR and rs25531, and Parkinson's disease (PD) remains to be further defined. We investigated this relationship in a Chinese cohort that comprised 504 PD patients and 504 controls. A total of 8 haplotypes and 14 genotypes of SLC6A4 were found in this population including a new variant of 5-HTTLPR, that is, 20G. Our results...

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PMID: 24684793
DOI: 10.1016/j.neurobiolaging.2014.03.002

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