Article
Serotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: preliminary findings.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Dec 2010
Lorenzi Cristina, Marcone Alessandra, Pirovano Adele, Marino Elena, Cordici Francesco, Cerami Chiara, Delmonte Dario, Cappa Stefano F, Bramanti Placido, Smeraldi Enrico
Abstract excerpt
Serotonergic transmission impairment and abnormal phosphorylation of tau protein have been implicated in the physiopathology of Alzheimer's disease (AD) and frontotemporal lobar dementia (FTLD). Associations between a functional polymorphism (5-HTTLPR), in the promoter region of the serotonin tra...
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