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Article

The serotonin transporter in Alzheimer's and Parkinson's disease.

Journal of neural transmission. Supplementum - 1 Jan 2000

Mössner R, Schmitt A, Syagailo Y, Gerlach M, Riederer P, Lesch K P

Abstract excerpt

The etiology of late-onset Alzheimer's disease (AD) and idiopathic Parkinson's disease (PD) is not known. In both disorders there is an extensive degeneration of serotonergic neurons, with corresponding losses of the serotonin (5HT) transporter (5HTT), which is responsible for the reuptake of 5HT from the synaptic cleft. An increasing body of evidence indicates that allelic variation of the 5HTT gene promoter...

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PMID: 11205152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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