Article
Association study to evaluate the serotonin transporter and apolipoprotein E genes in frontotemporal lobar degeneration in Italy.
Journal of human genetics - 1 Jan 2008
Albani Diego, Prato Francesca, Fenoglio Chiara, Batelli Sara, Dusi Sabrina, De Mauro Stefania, Polito Letizia, Lovati Carlo, Galimberti Daniela, Mariani Claudio, Scarpini Elio, Forloni Gianluigi
Abstract excerpt
Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder characterized by behavioral and language disturbances. We performed a case-control association study in the Italian population to assess the relevance for FTLD genetic susceptibility of the serotonin (5-HT) transporter gene-linked polymorphic region [rs4795541, alias short (S)/long (L)] an in/del polymorphism of the promoter...
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