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Article

Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo.

Molecular and cellular biochemistry - 1 Jul 2014

Tafrova Juliana I, Tafrov Stefan T

Abstract excerpt

The primary structure of Histone Acetyltransferase 1 (Hat1) has been conserved throughout evolution; however, despite its ubiquity, its cellular function is not well characterized. To study its in vivo acetylation pattern and function, we utilized shRNAmir against Hat1 expressed in the well-substantiated HeLa (human cervical cancer) cell line. To reduce the interference by enzymes with similar HAT specificity, we...

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PMID: 24682716
DOI: 10.1007/s11010-014-2036-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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