Article
Esa1p is an essential histone acetyltransferase required for cell cycle progression.
Molecular and cellular biology - 1 Apr 1999
Clarke A S, Lowell J E, Jacobson S J, Pillus L
Abstract excerpt
Histones are dynamically modified during chromatin assembly, as specific transcriptional patterns are established, and during mitosis and development. Modifications include acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation, but the biological significance of each of these is not well understood. For example, distinct acetylation patterns correlate with nucleosome formation and with...
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