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Article

Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease.

Neurobiology of aging - 1 Aug 2014

Gaisler-Salomon Inna, Kravitz Efrat, Feiler Yulia, Safran Michal, Biegon Anat, Amariglio Ninette, Rechavi Gideon

Abstract excerpt

Adenosine to inosine (A-to-I) RNA editing is a base recoding process within precursor messenger RNA, catalyzed by members of the adenosine deaminase acting on RNA (ADAR) family. A notable example occurs at the Q/R site of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptor subunit GluA2. Abnormally, low editing at this site leads to excessive calcium influx and cell death. We studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24679603
DOI: 10.1016/j.neurobiolaging.2014.02.018

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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