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Article

Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.

Neuroscience - 30 May 2014

Gao R, Du Y, Wang L, Nomura Y, Satar G, Gordon D, Gurevitz M, Goldin A L, Dong K

Abstract excerpt

Tetrodotoxin-sensitive persistent sodium currents, INaP, that activate at subthreshold voltages, have been detected in numerous vertebrate and invertebrate neurons. These currents are believed to be critical for regulating neuronal excitability. However, the molecular mechanism underlying INaP is controversial. In this study, we identified an INaP with a broad range of voltage dependence, from -60mV to 20mV, in a...

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Identifiers

PMID: 24662849
DOI: 10.1016/j.neuroscience.2014.03.028
PMCID: PMC4482340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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