Article
Hmga2 is required for canonical WNT signaling during lung development.
BMC biology - 24 Mar 2014
Singh Indrabahadur, Mehta Aditi, Contreras Adriana, Boettger Thomas, Carraro Gianni, Wheeler Matthew, Cabrera-Fuentes Hector A, Bellusci Saverio, Seeger Werner, Braun Thomas, Barreto Guillermo
Abstract excerpt
BACKGROUND: The high-mobility-group (HMG) proteins are the most abundant non-histone chromatin-associated proteins. HMG proteins are present at high levels in various undifferentiated tissues during embryonic development and their levels are strongly reduced in the corresponding adult tissues, where they have been implicated in maintaining and activating stem/progenitor cells. Here we deciphered the role of the...
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