Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging roles for HMGA2 in colorectal cancer

14 Oct 2020

Abstract excerpt

HMGA2 (High Mobility Group AT-hook 2) has been reported to promote colorectal cancer (CRC) development by regulating the transcription of target genes. It participates in nearly all aspects of cellular processes, including cell transformation, proliferation, apoptosis, senescence, metastasis, epithelial-to-mesenchymal transition (EMT), DNA repair and stem cell self-renewal. In the past decades, a group of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Genetic factors in colorectal cancer
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33069103
DOI: 10.1016/j.tranon.2020.100894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging roles for HMGA2 in colorectal cancerPMID 33069103Read ↗

HMGA2 promotes intestinal tumorigenesis by facilitating MDM2‐mediated ubiquitination and degradation of p53Semantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Transcriptional activation of FN1 and IL11 by HMGA2 promotes the malignant behavior of colorectal cancerSemantic proximity Read ↗

HMGA1 in cancer: Cancer classification by locationSemantic proximity Read ↗

High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial NeoplasiaSemantic proximity Read ↗

HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitmentSemantic proximity Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer.Semantic proximity Read ↗

Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transitionSemantic proximity Read ↗

HMGA2 rs968697 T > C polymorphism is associated with the risk of colorectal cancer.Semantic proximity Read ↗

High-Mobility Group A2 Protein Modulates hTERT Transcription To Promote TumorigenesisSemantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.