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Article

Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.

Blood - 2 Oct 2014

Lam Kentson, Muselman Alexander, Du Randal, Harada Yuka, Scholl Amanda G, Yan Ming, Matsuura Shinobu, Weng Stephanie, Harada Hironori, Zhang Dong-Er

Abstract excerpt

RUNX1 is a master transcription factor in hematopoiesis and mediates the specification and homeostasis of hematopoietic stem and progenitor cells (HSPCs). Disruptions in RUNX1 are well known to lead to hematologic disease. In this study, we sought to identify and characterize RUNX1 target genes in HSPCs by performing RUNX1 chromatin immunoprecipitation with high-throughput sequencing (ChIP-seq) using a murine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25150295
DOI: 10.1182/blood-2014-02-554543
PMCID: PMC4183983

Genes

RUNX1
HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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