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Article

HMGA2 participates in transformation in human lung cancer.

Molecular cancer research : MCR - 1 May 2008

Di Cello Francescopaolo, Hillion Joelle, Hristov Alexandra, Wood Lisa J, Mukherjee Mita, Schuldenfrei Andrew, Kowalski Jeanne, Bhattacharya Raka, Ashfaq Raheela, Resar Linda M S

Abstract excerpt

Although previous studies have established a prominent role for HMGA1 (formerly HMG-I/Y) in aggressive human cancers, the role of HMGA2 (formerly HMGI-C) in malignant transformation has not been clearly defined. The HMGA gene family includes HMGA1, which encodes the HMGA1a and HMGA1b protein isoforms, and HMGA2, which encodes HMGA2. These chromatin-binding proteins function in transcriptional regulation and...

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Share to Carcinoma, Non-Small-Cell Lung
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Chromatin

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 18505920
DOI: 10.1158/1541-7786.MCR-07-0095
PMCID: PMC3086547

Genes

HMGA2
HMGA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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