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Article

Single nucleotide polymorphisms at the PRR3, ABCF1, and GNL1 genes in the HLA class I region are associated with Graves' ophthalmopathy in a gender-dependent manner.

Ophthalmology - 1 Oct 2014

Liu Yu-Huei, Chen Yi-Ju, Wu Hsin-Hung, Wang Tzu-Yuan, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVE: To investigate whether a conserved HLA class I region influenced the development of Graves' ophthalmopathy (GO) in patients with Graves' disease (GD) in a Taiwan-Chinese population. DESIGN: Case-control study. PARTICIPANTS: Four hundred sixty-eight Taiwan-Chinese patients with GD; 200 of these patients had GO, whereas 268 patients did not. METHODS: Five single nucleotide polymorphisms (SNPs) between...

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Source

Identifiers

PMID: 24908204
DOI: 10.1016/j.ophtha.2014.04.027

Genes

PRR3
GNL1
ABCF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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