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Transcriptional switching in macrophages associated with the peritoneal foreign body response

18 Mar 2014

Abstract excerpt

We previously demonstrated that myeloid cells are the source of fibrotic tissue induced by foreign material implanted in the peritoneal cavity. This study utilised the MacGreen mouse, in which the Csf1r promoter directs myeloid-specific enhanced green fluorescent protein (EGFP) expression, to determine the temporal gene expression profile of myeloid subpopulations recruited to the peritoneal cavity to encapsulate...

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PMID: 24638066
DOI: 10.1038/icb.2014.19

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