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Live imaging the Foreign Body Response reveals how dampening inflammation reduces fibrosis

2018-12-17

Abstract excerpt

Implanting biomaterials such as surgical sutures leads to wound inflammation and a Foreign Body Response (FBR), which can result in scarring and ultimately biomaterial rejection. To investigate the cell and signalling events that underlie FBR, we use live imaging of zebrafish reporter lines to observe how inflammation and angiogenesis differ between a healthy acute wound versus suture implantation. We observe infl...

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Literature Corpus work
6686c25d-6ce8-5b0e-921c-e74ee3a27935
DOI
10.1101/498444
Open publication

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Live imaging the Foreign Body Response reveals how dampening inflammation reduces fibrosisDOI 10.1101/498444
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