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Article

Macrophage reaction against biomaterials in the mouse model - Phenotypes, functions and markers.

Acta biomaterialia - 1 Oct 2016

Klopfleisch R

Abstract excerpt

UNLABELLED: The foreign body reaction (FBR) is a response of the host tissue against more or less degradation-resistant foreign macromolecular material. The reaction is divided into five different phases which involve most aspects of the innate and the adaptive immune system: protein adsorption, acute and chronic inflammation, foreign body giant cell formation and fibrosis. It is long known, that macrophages play...

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PMID: 27395828
DOI: 10.1016/j.actbio.2016.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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