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Article

Fractional factorial design to investigate stromal cell regulation of macrophage plasticity.

Biotechnology and bioengineering - 1 Nov 2014

Barminko Jeffrey A, Nativ Nir I, Schloss Rene, Yarmush Martin L

Abstract excerpt

Understanding the regulatory networks which control specific macrophage phenotypes is essential in identifying novel targets to correct macrophage mediated clinical disorders, often accompanied by inflammatory events. Since mesenchymal stromal cells (MSCs) have been shown to play key roles in regulating immune functions predominantly via a large number of secreted products, we used a fractional factorial approach...

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Identifiers

PMID: 24891120
DOI: 10.1002/bit.25282
PMCID: PMC5928506

Genes

MSC
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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