Article
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Journal of cellular and molecular medicine - 1 Sept 2020
Xu Wang-Dong, Liu Xiao-Yan, Su Lin-Chong, Huang An-Fang
Abstract excerpt
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disorder. MASP2 is a mediator that plays an important role in complement system. As dysregulation of the complement system has been demonstrated to correlate with SLE pathogenesis, the role of MASP2 in lupus has not been widely discussed. In the present study, serum levels of MASP2 were evaluated in 61 lupus patients and 98 healthy controls...
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