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Ficolin-1 and ficolin-3 polymorphisms and susceptibility to rheumatoid arthritis.

Autoimmunity - 1 Nov 2020

Pieczarka Cristhine, Andrade Fabiana Antunes, Catarino Sandra Jeremias, Lidani Kárita Cláudia Freitas, Bavia Lorena, Tizzot Regina, Skare Thelma, de Messias-Reason Iara Jose

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disease, which compromises the synovial membrane resulting in chronic inflammation. Ficolins are key proteins of the lectin pathway of complement able to recognize pathogen-associated molecular patterns, apoptotic cells, and cellular debris mediating the clearance by phagocytes. High ficolin-1 and ficolin-3 levels have been observed in RA patients, however, the influence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32820945
DOI: 10.1080/08916934.2020.1809654

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