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Article

Association of MASP2 polymorphisms and protein levels with rheumatic fever and rheumatic heart disease.

Human immunology - 1 Dec 2014

Catarino Sandra Jeremias dos Santos, Boldt Angelica Beate Winter, Beltrame Marcia Holsbach, Nisihara Renato Mitsunori, Schafranski Marcelo Derbli, de Messias-Reason Iara Jose

Abstract excerpt

MASP-2 is a key protein of the lectin pathway of complement system. Several MASP2 polymorphisms were associated with MASP-2 serum levels or functional activity. Here we investigated a possible association between MASP2 polymorphisms and MASP-2 serum levels with the susceptibility to rheumatic fever (RF) and rheumatic heart disease (RHD). We haplotyped 11 MASP2 polymorphisms with multiplex sequence-specific PCR in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25318078
DOI: 10.1016/j.humimm.2014.10.003

Genes

MASP2
RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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