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Article

Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.

Acta neuropathologica communications - 13 Mar 2014

Bétemps Dominique, Verchère Jérémy, Brot Sébastien, Morignat Eric, Bousset Luc, Gaillard Damien, Lakhdar Latifa, Melki Ronald, Baron Thierry

Abstract excerpt

BACKGROUND: The accumulation of misfolded proteins appears as a fundamental pathogenic process in human neurodegenerative diseases. In the case of synucleinopathies such as Parkinson's disease (PD) or dementia with Lewy bodies (DLB), the intraneuronal deposition of aggregated alpha-synuclein (αS) is a major characteristic of the disease, but the molecular basis distinguishing the disease-associated protein (αSD)...

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Identifiers

PMID: 24624994
DOI: 10.1186/2051-5960-2-29
PMCID: PMC4007641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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