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Article

Single nucleotide polymorphic macrophage cytokine regulation by Mycobacterium tuberculosis and drug treatment.

Pharmacogenomics - 1 Mar 2014

Singh Amit K, Yadav Awadh Bihari, Garg Rajiv, Misra Amit

Abstract excerpt

AIM: To investigate the survival of Mycobacterium tuberculosis in primary macrophages with SNPs affecting cytokine secretion under treatment with drugs in solution or microparticles. MATERIALS & METHODS: Volunteers were typed for TNF (-308G/A), IL-10 (-1082A/G) and IL-4 (-590C/T). Monocyte-derived macrophages (MDMs) were infected in vitro. Cytokine secretion and survival of intracellular bacilli were estimated....

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Source

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PMID: 24624917
DOI: 10.2217/pgs.13.240

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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