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Article

Differential serum cytokine levels are associated with cytokine gene polymorphisms in north Indians with active pulmonary tuberculosis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2011

Abhimanyu, Mangangcha Irengbam Rocky, Jha Pankaj, Arora Komal, Mukerji Mitali, Banavaliker Jayant Nagesh, Brahmachari Vani, Bose Mridula

Abstract excerpt

Globally only 5-10% of people encountering Mycobacterium tuberculosis have a lifetime risk of active disease indicating a strong host genetic bias towards development of tuberculosis. In the current study we investigated genotype variants pertaining to five cytokine genes namely IFNG, TNFA, IL4, IL10 and IL12 in the north Indian population with active pulmonary tuberculosis (APTB) and correlated the serum...

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Share to Cytokines
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 21463712
DOI: 10.1016/j.meegid.2011.03.017

Genes

IFNG
TNF

Provenance

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