Article
Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts.
PloS one - 1 Jan 2015
Joshi Lavanya, Ponnana Meenakshi, Sivangala Ramya, Chelluri Lakshmi Kiran, Nallari Prathiba, Penmetsa Sitaramaraju, Valluri Vijayalakshmi, Gaddam Sumanlatha
Abstract excerpt
BACKGROUND: Household contacts of diagnostically established tuberculosis (TB) patients are highly susceptible to disease development. It is surmised that cytokines perhaps play a synergistic and a prognostic role in the activation of the otherwise latent infection in these house hold contacts. Evaluation of the cytokines and any of their inherent polymorphisms might provide a useful diagnostic tool in evaluating...
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