Article
Recombinant human lactoferrin modulates human PBMC derived macrophage responses to BCG and LPS.
Tuberculosis (Edinburgh, Scotland) - 1 Dec 2016
Hwang Shen-An, Kruzel Marian L, Actor Jeffrey K
Abstract excerpt
Lactoferrin, an iron-binding glycoprotein found in mammalian mucosal secretions and granules of neutrophils, possesses several immune modulatory properties. Published reports indicate that lactoferrin enhances the efficacy of the tuberculosis vaccine, BCG (Bacillus Calmette Guerin), both by increasing macrophage and dendritic cell ability to stimulate receptive T cells and by modulating the inflammatory response....
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