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Article

IL-32 Is a Host Protective Cytokine against <i>Mycobacterium tuberculosis</i> in Differentiated THP-1 Human Macrophages

26 Feb 2010

Abstract excerpt

Macrophages provide a first line of defense against Mycobacterium tuberculosis. However, in instances where macrophage activation for killing is suboptimal, M. tuberculosis is capable of surviving intracellularly. IL-32 is a recently described cytokine induced by M. tuberculosis in a variety of cell types including human monocytes and macrophages. In this study, we investigated the biological significance of...

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PMID: 20190143
DOI: 10.4049/jimmunol.0901913

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