Article
HLA-DRB1*1501 and VDR polymorphisms and survival of Mycobacterium tuberculosis in human macrophages exposed to inhalable microparticles.
Pharmacogenomics - 1 Apr 2013
Singh Amit K, Abhimanyu, Yadav Awadh B, Sharma Sandeep, Garg Rajiv, Bose Mridula, Misra Amit
Abstract excerpt
AIM: We examined whether HLA-DRB1*1501 and four VDR SNPs influence the macrophage response to infection with Mycobacterium tuberculosis (Mtb) via innate immune versus drug treatment or drug delivery mechanisms. MATERIALS & METHODS: Monocyte-derived macrophages from 24 healthy donors were infected...
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