Article
Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis genotypes.
Clinical and experimental immunology - 1 Jun 2005
Chacón-Salinas R, Serafín-López J, Ramos-Payán R, Méndez-Aragón P, Hernández-Pando R, Van Soolingen D, Flores-Romo L, Estrada-Parra S, Estrada-García I
Abstract excerpt
It has been shown recently that different genotypes of Mycobacterium tuberculosis induce distinct immune responses in the host, as reflected by variations in cytokine and iNOS expression. Because these molecules are probably regulated by multiple factors in vivo this complex phenomenon was partially analysed by assessing cytokine and iNOS expression by real-time polymerase chain reaction (PCR) and enzyme-linked...
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