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Article

Modulation of human monocyte/macrophage activity by tocilizumab, abatacept and etanercept: An in vitro study.

European journal of pharmacology - 5 Jun 2016

Obeng Joyce Afrakoma, Amoruso Angela, Camaschella Gian Luca Ermanno, Sola Daniele, Brunelleschi Sandra, Fresu Luigia Grazia

Abstract excerpt

Tocilizumab, etanercept and abatacept are biological drugs used in the therapy of Rheumatoid Arthritis (RA). Their mechanism of action is well documented but their direct effects on human monocytes/macrophages have not been fully investigated. The objective of this study was to evaluate in vitro the influence of these drugs on monocytes/macrophages from healthy volunteers. Human monocytes were isolated from...

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Share to Abatacept
Share to Antibodies, Monoclonal, Humanized

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Enzymologic

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Share to Matrix Metalloproteinase 9

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Source

Identifiers

PMID: 26997366
DOI: 10.1016/j.ejphar.2016.03.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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